The legalization of medical and recreational cannabis products across Canada and many US states has led to an increased demand for safe cannabis products. Health Canada has set stringent regulations for testing pesticides in cannabis products, both in terms of the number of pesticides required to be analyzed and the relatively low limits of quantification that must be achieved.
To fulfil these mandatory testing requirements, we need quantitative and confirmatory methods that can provide reliable coverage and robust performance for the entire list of pesticides.
Although most of the target pesticides are amenable to LC-MS/MS analysis, selected pesticides require much lower detection limits that can be achieved using GC-MS/MS methods. We will discuss how these complimentary techniques and the benefits of atmospheric pressure GC (APGC-MS/MS) can be used to provide a suitable determination of all pesticides currently regulated by Health Canada at the recommended limits of quantitation.
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