This application note describes a method for the separation of the Δ10-THC and Δ6a,10a-THC isomers using a chiral HPLC stationary phase. The use of a chiral column under normal-phase liquid chromatography conditions provides an analytical method to fully separate these THC isomers for identification and accurate determination of potency.
The method utilizes a simple extraction procedure with no additional sample clean-up and is suitable for analysis of the major neutral cannabinoids as well as cannabinoid acids with high sensitivity and selectivity of detection.
The method is suitable for analysis of the major neutral cannabinoids such as THC, CBD, CBN and CBG as well cannabinoid acids THCA-A and CBDA with high sensitivity and selectivity of detection.
Pickering have developed an easy and sensitive method to analyze Aflatoxins B1, B2, G1, G2, and Ochratoxin A in cannabis plant and edible products.
Pickering Laboratories have developed an easy and sensitive method to analyze Aflatoxins B1, B2, G1, G2, and Ochratoxin A in hemp and hemp-containing edible products.
Download this app note to discover a method that provides fast multi-element analysis, good control of spectral overlaps and measurements over a wide dynamic range.
Hemp and cannabis are strains of the Cannabis sativa plant. They are known to accumulate heavy metals in their roots, shoots, buds and seeds. Due to this ability, hemp has been used for the remediation of contaminated soil (phytoremediation and phytoextraction).
Quantitative analysis of mycotoxins commonly involves sampling, sample preparation, extraction and cleanup followed by chromatographic methods such as GC and HPLC. The matrix complexity of cannabis often makes sample cleanup methods used for common commodities ineffective.
There is a demand for a better, more accurate and reproducible methodology to test cannabinoid potency in edibles in order to meet regulatory requirements, which vary greatly depending on country and/or state. Each food type (chocolate, brownies, cookies, candies, beverages, etc) has specific challenges, all directly impacting results, uptime and maintenance of analytical instrumentation.